cGMP Vero Cell Banking

Vero cells are a lineage of cells used in cell cultures. The 'Vero' lineage was isolated from kidney epithelial cells extracted from an African green monkey. They have been used for producing viral vaccines for humans ever since microcarrier-based cell culture processes were developed in the 1970s. They have been approved for Polio, Smallpox, Rabies, Japanese Encephalitis, rotavirus, Vaccinia, and Influenza vaccines and are used for the development of new vaccines and vaccine vectors, such as Vaccinia, Polio, Ross River, West Nile, Chikungunya, tick-borne encephalitis virus (TBE), Hepatitis A, SARS-Coronavirus, Coronavirus, etc.

Creative Bioarray provides a cGMP-compliant Vero cell bank by following the industry-standard cell bank system to help our customers worldwide. By using cGMP Vero cell banking services, our clients can avoid cumbersome and time-intensive production of their cell bank and eliminate associated risks and costs. Thus, our clients can immediately start the cGMP Vero cell bank according to a fully tested manufacturing workflow.

Our Cell Services Cover the Complete Lifecycle of a Cell Bank

• Testing of developed cell lines prior to bank construction. Our service also allows customers to provide their cell lines.
• Cell banking for master cell banks (MCB) under cGMP conditions. The corresponding Vero cGMP master cell bank is available and can be transferred to a customer or a CMO to allow unlimited manufacturing and complete manufacturing independence.
• Cell banking for working cell banks (WCB) under cGMP conditions, which is available to immediately start manufacturing of clinical trial material at your CMO. Quality control tests via DNA profiling techniques are performed under cGMP to confirm that the MCB and the WCB are genetically identical and to ensure the WCB is free of contaminants.
• Complete validation and release of MCB and WCB in compliance with national regulatory requirements.
• Long-term storage of cell banks in a secure, controlled, and monitored environment with a reasonable amount of inventory and freezing stability guarantee. In addition, cell banks are divided and stored in separate freezers to prevent loss due to freezer malfunction.

Advantages of Our Vero Cell Banking Services

• Dedicated cGMP licensed facility.
• Production of MCB and WCB cells under serum/animal-free media conditions.
• Fast and easy access to a working bank vial to evaluate virus growth on Vero cell banks including protocols and technical support.
• Cell bank (or individual cryovials) shipment to any destination worldwide.
• Flexibility of transfer to any CMO for product manufacture.

Creative Bioarray provides cost-effective, high-quality, and hassle-free services to our customers worldwide. We provide our clients with direct access to our experts and prompt responses to their questions. If you are interested in our services or have any questions, please feel free to contact us or make an online inquiry.