Cat. No.: GENE0004

IFNG

Description Interferon Gamma
Category Protein Coding
GIFtS 47
GC id GC12M068154
Score 44.69
Entrez Gene Summary This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
GeneCards Summary IFNG (Interferon Gamma) is a Protein Coding gene. Diseases associated with IFNG include Immunodeficiency 69 and Hepatitis C Virus. Among its related pathways are Bacterial infections in CF airways and Immune response IFN alpha/beta signaling pathway. Gene Ontology (GO) annotations related to this gene include cytokine activity and interferon-gamma receptor binding.
Gene Database GeneCards: The Human Gene Database
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