Description | Interferon Gamma |
Category | Protein Coding |
GIFtS | 47 |
GC id | GC12M068154 |
Score | 44.69 |
Entrez Gene Summary | This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015] |
GeneCards Summary | IFNG (Interferon Gamma) is a Protein Coding gene. Diseases associated with IFNG include Immunodeficiency 69 and Hepatitis C Virus. Among its related pathways are Bacterial infections in CF airways and Immune response IFN alpha/beta signaling pathway. Gene Ontology (GO) annotations related to this gene include cytokine activity and interferon-gamma receptor binding. |
Gene Database | GeneCards: The Human Gene Database |
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