| Description | Interleukin 6 |
| Category | Protein Coding |
| GIFtS | 48 |
| GC id | GC07P022725 |
| Score | 45.17 |
| Entrez Gene Summary | This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). [provided by RefSeq, Aug 2020] |
| GeneCards Summary | IL6 (Interleukin 6) is a Protein Coding gene. Diseases associated with IL6 include Rheumatoid Arthritis, Systemic Juvenile and Kaposi Sarcoma. Among its related pathways are Bacterial infections in CF airways and Phospholipase-C Pathway. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and growth factor activity. |
| Gene Database | GeneCards: The Human Gene Database |
| Price | Inquiry |
