| Description | As part of the fluid-blood barrier in the stria vascularis, the cochlear microvascular endothelial cells, along with perivascular resident macrophate-type melanocytes (PVM/Ms) and cochlear pericytes, are important for maintaining the inner ear homeostasis. The cochlear microvascular endothelial cells form tight junctions and primarily sustains the barrier integrity. With all three primary cells available, co-culture of the cell types is useful in studying the underlying causes of vascular dysfunction-related hearing loss. |
| Tissue/Organ/Organ System | Auditory |
| Size | 5*105 cells/1.0 ml |
| Species | Mouse |
| Shipping Info | Dry Ice |
| Storage Conditions | Liquid Nitrogen |
| Growth Properties | Adherent |
| Categories | Primary Cells |
| Applications | For Research Use Only |
| Cell Morphology | Cuboidal, Elongated, Flat |
| Donor Age | 10- to 15-day-old |
| Donor Gender | Donor Info Not Disclosed |
| Expression Profile | VWF |
| Isolation Method | Mouse Primary Cochlear Endothelial Cells were isolated and purified by flow cytometry based on isolectin B4 (BSI-B4) sorting. Sorted cells were validated with anti-von Willebrand factor (vWF) antibody in immunohistochemical staining. |
| Price | Inquiry |
