| Description | Human Pulmonary Artery Smooth Muscle Cells (HPASMC) have been used to show: Anti-tumor drugs can selectively target remodeled pulmonary blood vessels, but cannot target normal blood vessels Serotonin induces its growth and activates BMP receptors IL-23 promotes the growth of pulmonary vascular SMC through a signal transduction mechanism involving NADPH oxidase-dependent oxidation Targeted gene transcription can inhibit pulmonary hypertension induced by pulmonary artery wall thickening By inducing the expression of known cell growth inhibitors, cell growth can be inhibited by trans-retinoic acid, Retinoic acid and its receptor may be involved in cell growth and pulmonary vascular remodeling Iron chelation has an effect on vascular remodeling and leads to the development of pulmonary hypertension due to ROS activity |
| Size/Quantity | T-25 Flask/T-75 Flask/24/well/96 Well |
| Quality Control | No bacteria, yeast, fungi, mycoplasma, virus |
| Application | For research use only |
| Tissue | Normal healthy human pulmonary artery |
| Character | Smooth muscle specific α-actin positive |
| Bioassay | Attach, spread, proliferate in Growth Med |
| Cryovial | 500,000 HPASMC frozen in Basal Medium w/ 10% FBS, 10% DMSO |
| Kit | Cryovial frozen HPASMC (352-05a), Growth Medium (311-500), Subcltr Rgnt Kit (090K) |
| Proliferating | Shipped in Gr Med, 3rd psg (flasks or plates) |
| Doublings | At least 16 |
| Price | Inquiry |
