Cultured cells are used for the manufacturing of biologics such as vaccines, therapeutic proteins and antibodies, and cell therapy products. Our cell banking and characterization services provide a cGMP-compliant and cost-efficient basis for your project. Creative Bioarray provides tailored solutions and enables your high-potential molecules to become a market success. Our integrated services from cell banking to process development of cell therapy products support our clients' challenges.
- Vaccines are made from dead (inactivated) or modified (attenuated live) whole microbes, or from inactivated or recombinant parts of microbes that are responsible for disease (such as toxins or surface proteins).
- Vaccines are produced on a large scale as they need to be administered to large populations of children and adults to be effective as a public health tool. This large-scale production is often a challenge.
- Creative Bioarray now provides strong cell support in the process development for vaccine production to our customers worldwide, such as CHO, HEK293, mammalian cell, and insect cell banking services.
Fig.1 Process development.
Process Development for Recombinant Proteins
- Recombinant proteins have been produced for over 30 years. Recombinant proteins are proteins encoded by recombinant DNA that have been cloned in an expression vector that supports the expression of the gene and the translation of messenger RNA.
- We offer cell support services in the process development for recombinant proteins to help our customers worldwide, including CHO, HEK293, and insect cell banking services.
Process Development for Protein Conjugates
Protein conjugates can be used for a variety of applications including protein blotting, ELISA, and immunotoxins for drug delivery. We offer high-quality cGMP-compliant CHO, NS0, Sp2/0, and other cell banking services as strong support for protein manufacturing in protein conjugates processing.
Process Development for Fc-fusion Proteins
- Fc-fusion proteins are bioengineered polypeptides that join the crystallizable fragment (Fc) domain of an antibody with another biologically active protein domain or peptide to generate a molecule with unique structure-function properties and significant therapeutic potential.
- We provide cell support services, including CHO, HEK293, NS0, SP2/0, and VERO cell banking services, in the process development for Fc-fusion proteins manufacturing to help our customers worldwide.
Process Development for Monoclonal Antibodies
- Monoclonal antibodies (also called moAbs or mAbs) are a series of identical antibodies produced by a single clone of B cell, which has been used to treat cancer, organ transplant rejection, inflammatory and autoimmune disorders, infections, and so on.
- We provide cGMP-compliant NS0 and CHO cell banking services as a strong support to express monoclonal antibodies to our global clients in research of monoclonal antibodies.
Process Development for Bispecific Antibodies
- Bispecific antibodies (BsAbs) contain two different antigen-binding sites. They are a type of reconstructive molecule that can recognize two different epitopes. BsAb aims to treat multifaceted, complex diseases by engaging two disease targets with one molecule.
- We provide cGMP-compliant CHO and insect cell banking services as strong support for monoclonal antibodies, which ensure that a uniform and intact cell population is maintained and that sufficient material supply is provided for the process development.
Process Development for Antibody Drug Conjugates
- Antibody-drug conjugates (ADCs) are highly targeted biopharmaceutical drugs that combine monoclonal antibodies specific to surface antigens present on particular tumor cells with highly potent anti-cancer agents linked via a chemical linker.
- We provide cGMP-compliant CHO, NS0, Sp2/0, and other cell banking services as strong support for antibody manufacturing in ADC processing.
Process Development for Therapeutic Oligonucleotides
We provide various stem cell banking services as strong support for studies of therapeutic oligonucleotide delivery, including hematopoietic stem cell banking, mesenchymal stem cell banking, and iPS cell banking.
Creative Bioarray is always devoted to providing high-quality and satisfactory service to our customers. If you are interested in our services or have any questions, please feel free to contact us or make an online inquiry.
